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February 9, 2009

Wikipedia: Posterior cortical atrophy

Filed under: — admin @ 11:10 pm

Posterior cortical atrophy (PCA), also called Benson’s syndrome, is the visual variant of Alzheimer’s disease[1]. The disease causes shrinkage (atrophy) of the back (posterior) part of the brain (cortex). It is a clinical syndrome in which complex visual processing is progressively disrupted owing to a neurodegenerative disorder. PCA was first described by Franck Benson in 1988.

Renowned fantasy fiction writer Sir Terry Pratchett OBE has been diagnosed with this disease.[2]


  1. ^ Nestor PJ, Caine D, Fryer TD, Clarke J, Hodges JR: The topography of metabolic deficits in posterior cortical atrophy (the visual variant of Alzheimer’s disease) with FDG-PET. J Neurol Neurosurg Psychiatry 2003; 74:1521–1529
  2. ^ “Terry Pratchett pledges $1 million to Alzheimer’s research”. Alzheimer’s Research Trust. 2008-03-13. 

External links

  • Benson’s syndrome or Posterior cortical atrophy — orphanet
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